General Structure Information
| PDB ID | 2v60 |
| HGNC Gene Label(s) | MAOB |
| Structure Name | structure of human mao b in complex with the selective inhibitor 7-(3-chlorobenzyloxy)-4-carboxaldehyde-coumarin |
| Resolution | 2.0Å |
| Reference | AUTH C.BINDA,J.WANG,L.PISANI,C.CACCIA,A.CAROTTI,AUTH 2 P.SALVATI,D.E.EDMONDSON,A.MATTEVITITL STRUCTURES OF HUMAN MONOAMINE OXIDASE B COMPLEXESTITL 2 WITH SELECTIVE NONCOVALENT INHIBITORS: SAFINAMIDETITL 3 AND COUMARIN ANALOGS.REF J.MED.CHEM. V. 50 5848 2007REFN ISSN 0022-2623PMID 17915852DOI 10.1021/JM070677Y |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 499 |
| Number Of SNVs | 61 |
| Number Of Permutations | 17479 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.078 |
| p-value | 0.105 |
COSMIC
| Number Of Residues | 499 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1384 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.133 |
| p-value | 0.522 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 61 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | -0.21 |
| p-value | 0.303 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
