General Structure Information
| PDB ID | 4kfz |
| HGNC Gene Label(s) | LMO2 |
| Structure Name | crystal structure of lmo2 and anti-lmo2 vh complex |
| Resolution | 2.8Å |
| Reference | AUTH H.SEWELL,T.TANAKA,K.E.OMARI,E.J.MANCINI,A.CRUZ,AUTH 2 N.FERNANDEZ-FUENTES,J.CHAMBERS,T.H.RABBITTSTITL CONFORMATIONAL FLEXIBILITY OF THE ONCOGENIC PROTEIN LMO2TITL 2 PRIMES THE FORMATION OF THE MULTI-PROTEIN TRANSCRIPTIONTITL 3 COMPLEX.REF SCI REP V. 4 3643 2014REFN ESSN 2045-2322PMID 24407558DOI 10.1038/SREP03643 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 146 |
| Number Of SNVs | 32 |
| Number Of Permutations | 32164 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.111 |
| p-value | 0.942 |
COSMIC
| Number Of Residues | 146 |
| Number Of SNVs | 5 |
| Number Of Permutations | 491 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.1 |
| p-value | 0.896 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 32 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.288 |
| p-value | 0.746 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
