General Structure Information
| PDB ID | 4gbx |
| HGNC Gene Label(s) | HLA-DMB |
| Structure Name | crystal structure of an immune complex at ph 6.5 |
| Resolution | 3.0Å |
| Reference | AUTH W.POS,D.K.SETHI,M.J.CALL,M.S.SCHULZE,A.K.ANDERS,J.PYRDOL,AUTH 2 K.W.WUCHERPFENNIGTITL CRYSTAL STRUCTURE OF THE HLA-DM-HLA-DR1 COMPLEX DEFINESTITL 2 MECHANISMS FOR RAPID PEPTIDE SELECTION.REF CELL(CAMBRIDGE,MASS.) V. 151 1557 2012REFN ISSN 0092-8674PMID 23260142DOI 10.1016/J.CELL.2012.11.025 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 191 |
| Number Of SNVs | 41 |
| Number Of Permutations | 9448 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.028 |
| p-value | 0.366 |
COSMIC

Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC

Pathogenic Proximity Analysis
COSMIC PathProx Analysis

