General Structure Information
| PDB ID | 3n06 |
| HGNC Gene Label(s) | PRLR |
| Structure Name | a mutant human prolactin receptor antagonist h27a in complex with the extracellular domain of the human prolactin receptor |
| Resolution | 2.0Å |
| Reference | AUTH M.V.KULKARNI,M.C.TETTAMANZI,J.W.MURPHY,C.KEELER,D.G.MYSZKA,AUTH 2 N.E.CHAYEN,E.J.LOLIS,M.E.HODSDONTITL TWO INDEPENDENT HISTIDINES, ONE IN HUMAN PROLACTIN AND ONETITL 2 IN ITS RECEPTOR, ARE CRITICAL FOR PH-DEPENDENT RECEPTORTITL 3 RECOGNITION AND ACTIVATION.REF J.BIOL.CHEM. V. 285 38524 2010REFN ISSN 0021-9258PMID 20889499DOI 10.1074/JBC.M110.172072 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 205 |
| Number Of SNVs | 52 |
| Number Of Permutations | 31408 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.38 |
| p-value | 0.181 |