General Structure Information
| PDB ID | 1pvh |
| HGNC Gene Label(s) | LIF |
| Structure Name | crystal structure of leukemia inhibitory factor in complex with gp130 |
| Resolution | 2.5Å |
| Reference | AUTH M.J.BOULANGER,A.J.BANKOVICH,T.KORTEMME,D.BAKER,AUTH 2 K.C.GARCIATITL CONVERGENT MECHANISMS FOR RECOGNITION OF DIVERGENTTITL 2 CYTOKINES BY THE SHARED SIGNALING RECEPTOR GP130.REF MOL.CELL V. 12 577 2003REFN ISSN 1097-2765PMID 14527405DOI 10.1016/S1097-2765(03)00365-4 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 169 |
| Number Of SNVs | 51 |
| Number Of Permutations | 20092 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.235 |
| p-value | 0.253 |
COSMIC
| Number Of Residues | 169 |
| Number Of SNVs | 4 |
| Number Of Permutations | 96 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.167 |
| p-value | 0.822 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
