General Structure Information
| PDB ID | 1ni2 |
| HGNC Gene Label(s) | EZR |
| Structure Name | structure of the active ferm domain of ezrin |
| Resolution | 2.3Å |
| Reference | AUTH W.J.SMITH,N.NASSAR,A.P.BRETSCHER,R.A.CERIONE,AUTH 2 P.A.KARPLUSTITL STRUCTURE OF THE ACTIVE N-TERMINAL DOMAIN OFTITL 2 EZRIN. CONFORMATIONAL AND MOBILITY CHANGESTITL 3 IDENTIFY KEYSTONE INTERACTIONS.REF J.BIOL.CHEM. V. 278 4949 2003REFN ISSN 0021-9258PMID 12429733DOI 10.1074/JBC.M210601200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 296 |
| Number Of SNVs | 75 |
| Number Of Permutations | 12580 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.215 |
| p-value | 0.012 |
COSMIC
| Number Of Residues | 296 |
| Number Of SNVs | 4 |
| Number Of Permutations | 627 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.167 |
| p-value | 0.723 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 75 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 35.0 |
| K Statistic | 0.363 |
| p-value | 0.836 |