General Structure Information
| PDB ID | 1lm7 |
| HGNC Gene Label(s) | DSP |
| Structure Name | structures of two intermediate filament-binding fragments of desmoplakin reveal a unique repeat motif structure |
| Resolution | 3.0Å |
| Reference | AUTH H.J.CHOI,S.PARK-SNYDER,L.T.PASCOE,K.J.GREEN,AUTH 2 W.I.WEISTITL STRUCTURES OF TWO INTERMEDIATE FILAMENT-BINDINGTITL 2 FRAGMENTS OF DESMOPLAKIN REVEAL A UNIQUE REPEATTITL 3 MOTIF STRUCTURE.REF NAT.STRUCT.BIOL. V. 9 612 2002REFN ISSN 1072-8368PMID 12101406 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 238 |
| Number Of SNVs | 33 |
| Number Of Permutations | 4886 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.017 |
| p-value | 0.098 |
ClinVar
COSMIC
| Number Of Residues | 238 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1186 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.048 |
| p-value | 0.729 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
Cosmic vs. ExAC
| Number Of ExAC SNVs | 33 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.065 |
| p-value | 0.829 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
COSMIC PathProx Analysis
