General Structure Information
| PDB ID | 2bq8 |
| HGNC Gene Label(s) | ACP5 |
| Structure Name | crystal structure of human purple acid phosphatase with an inhibitory conformation of the repression loop |
| Resolution | 2.2Å |
| Reference | AUTH N.STRATER,B.JASPER,M.SCHOLTE,B.KREBS,A.P.DUFF,AUTH 2 D.B.LANGLEY,R.HAN,B.A.AVERILL,H.C.FREEMAN,J.M.GUSSTITL CRYSTAL STRUCTURES OF RECOMBINANT HUMAN PURPLETITL 2 ACID PHOSPHATASE WITH AND WITHOUT AN INHIBITORYTITL 3 CONFORMATION OF THE REPRESSION LOOP.REF J.MOL.BIOL. V. 351 233 2005REFN ISSN 0022-2836PMID 15993892DOI 10.1016/J.JMB.2005.04.014 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 304 |
| Number Of SNVs | 82 |
| Number Of Permutations | 8950 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.106 |
| p-value | 0.003 |
ClinVar
| Number Of Residues | 304 |
| Number Of SNVs | 3 |
| Number Of Permutations | 131 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.0 |
| p-value | 0.933 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 82 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.156 |
| p-value | 0.877 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
