General Structure Information
| PDB ID | 1g1q |
| HGNC Gene Label(s) | SELP |
| Structure Name | crystal structure of p-selectin lectin/egf domains |
| Resolution | 2.4Å |
| Reference | AUTH W.S.SOMERS,J.TANG,G.D.SHAW,R.T.CAMPHAUSENTITL INSIGHTS INTO THE MOLECULAR BASIS OF LEUKOCYTETITL 2 TETHERING AND ROLLING REVEALED BY STRUCTURES OF P-TITL 3 AND E-SELECTIN BOUND TO SLE(X) AND PSGL-1.REF CELL(CAMBRIDGE,MASS.) V. 103 467 2000REFN ISSN 0092-8674PMID 11081633DOI 10.1016/S0092-8674(00)00138-0 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 157 |
| Number Of SNVs | 41 |
| Number Of Permutations | 19762 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.274 |
| p-value | 0.158 |
COSMIC
| Number Of Residues | 157 |
| Number Of SNVs | 3 |
| Number Of Permutations | 107 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.333 |
| p-value | 0.926 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 41 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.54 |
| p-value | 0.348 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
