General Structure Information
| PDB ID | 1kwm |
| HGNC Gene Label(s) | CPB1 |
| Structure Name | human procarboxypeptidase b: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (tafi) |
| Resolution | 1.6Å |
| Reference | AUTH P.J.BARBOSA PEREIRA,S.SEGURA-MARTIN,B.OLIVA,AUTH 2 C.FERRER-ORTA,F.X.AVILES,M.COLL,F.X.GOMIS-RUTH,AUTH 3 J.VENDRELLTITL HUMAN PROCARBOXYPEPTIDASE B: THREE-DIMENSIONALTITL 2 STRUCTURE AND IMPLICATIONS FORTITL 3 THROMBIN-ACTIVATABLE FIBRINOLYSIS INHIBITOR (TAFI).REF J.MOL.BIOL. V. 321 537 2002REFN ISSN 0022-2836PMID 12162965DOI 10.1016/S0022-2836(02)00648-4 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 309 |
| Number Of SNVs | 85 |
| Number Of Permutations | 33016 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.251 |
| p-value | 0.186 |
COSMIC
| Number Of Residues | 309 |
| Number Of SNVs | 10 |
| Number Of Permutations | 9741 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.156 |
| p-value | 0.225 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 85 |
| Number Of COSMIC SNVs | 9 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.143 |
| p-value | 0.344 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
