General Structure Information
| PDB ID | 3se4 |
| HGNC Gene Label(s) | IFNAR1 |
| Structure Name | human ifnw-ifnar ternary complex |
| Resolution | 3.5Å |
| Reference | AUTH C.THOMAS,I.MORAGA,D.LEVIN,P.O.KRUTZIK,Y.PODOPLELOVA,A.TREJO,AUTH 2 C.LEE,G.YARDEN,S.E.VLECK,J.S.GLENN,G.P.NOLAN,J.PIEHLER,AUTH 3 G.SCHREIBER,K.C.GARCIATITL STRUCTURAL LINKAGE BETWEEN LIGAND DISCRIMINATION ANDTITL 2 RECEPTOR ACTIVATION BY TYPE I INTERFERONS.REF CELL(CAMBRIDGE,MASS.) V. 146 621 2011REFN ISSN 0092-8674PMID 21854986DOI 10.1016/J.CELL.2011.06.048 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 285 |
| Number Of SNVs | 79 |
| Number Of Permutations | 19148 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.021 |
| p-value | 0.32 |
COSMIC
| Number Of Residues | 285 |
| Number Of SNVs | 7 |
| Number Of Permutations | 4848 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.048 |
| p-value | 0.885 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 79 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | -0.185 |
| p-value | 0.869 |