General Structure Information
| PDB ID | 1fd0 |
| HGNC Gene Label(s) | RARG |
| Structure Name | isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the rargamma-selective retinoid sr11254 |
| Resolution | 1.38Å |
| Reference | AUTH B.KLAHOLZ,D.MORASTITL C-H…O HYDROGEN BONDS IN THE NUCLEAR RECEPTORTITL 2 RARGAMMA–A POTENTIAL TOOL FOR DRUG SELECTIVITY.REF STRUCTURE V. 10 1197 2002REFN ISSN 0969-2126PMID 12220491DOI 10.1016/S0969-2126(02)00828-6 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 235 |
| Number Of SNVs | 28 |
| Number Of Permutations | 11246 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.077 |
| p-value | 0.984 |
COSMIC
| Number Of Residues | 235 |
| Number Of SNVs | 4 |
| Number Of Permutations | 362 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.167 |
| p-value | 0.421 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 28 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.333 |
| p-value | 0.26 |