General Structure Information
| PDB ID | 1itv |
| HGNC Gene Label(s) | MMP9 |
| Structure Name | dimeric form of the haemopexin domain of mmp9 |
| Resolution | 1.95Å |
| Reference | AUTH H.CHA,E.KOPETZKI,R.HUBER,M.LANZENDORFER,AUTH 2 H.BRANDSTETTERTITL STRUCTURAL BASIS OF THE ADAPTIVE MOLECULARTITL 2 RECOGNITION BY MMP9.REF J.MOL.BIOL. V. 320 1065 2002REFN ISSN 0022-2836PMID 12126625DOI 10.1016/S0022-2836(02)00558-2 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 195 |
| Number Of SNVs | 34 |
| Number Of Permutations | 3724 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.029 |
| p-value | 0.769 |
COSMIC
| Number Of Residues | 195 |
| Number Of SNVs | 4 |
| Number Of Permutations | 497 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.167 |
| p-value | 0.43 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 34 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | -0.285 |
| p-value | 0.189 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
