General Structure Information
| PDB ID | 2h3n |
| HGNC Gene Label(s) | IGLL1 |
| Structure Name | crystal structure of a surrogate light chain (lambda5 and vpreb) homodimer |
| Resolution | 2.3Å |
| Reference | AUTH A.J.BANKOVICH,S.RAUNSER,Z.S.JUO,T.WALZ,M.M.DAVIS,AUTH 2 K.C.GARCIATITL STRUCTURAL INSIGHT INTO PRE-B CELL RECEPTORTITL 2 FUNCTIONREF SCIENCE V. 316 291 2007REFN ISSN 0036-8075PMID 17431183DOI 10.1126/SCIENCE.1139412 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 116 |
| Number Of SNVs | 47 |
| Number Of Permutations | 12704 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.02 |
| p-value | 0.94 |
COSMIC
| Number Of Residues | 116 |
| Number Of SNVs | 3 |
| Number Of Permutations | 27 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.667 |
| p-value | 0.328 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.653 |
| p-value | 0.304 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
