General Structure Information
| PDB ID | 1br9 |
| HGNC Gene Label(s) | TIMP2 |
| Structure Name | human tissue inhibitor of metalloproteinase-2 |
| Resolution | 2.1Å |
| Reference | AUTH A.TUUTTILA,E.MORGUNOVA,U.BERGMANN,Y.LINDQVIST,AUTH 2 K.MASKOS,C.FERNANDEZ-CATALAN,W.BODE,K.TRYGGVASON,AUTH 3 G.SCHNEIDERTITL THREE-DIMENSIONAL STRUCTURE OF HUMAN TISSUETITL 2 INHIBITOR OF METALLOPROTEINASES-2 AT 2.1 ATITL 3 RESOLUTION.REF J.MOL.BIOL. V. 284 1133 1998REFN ISSN 0022-2836PMID 9837731DOI 10.1006/JMBI.1998.2223 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 182 |
| Number Of SNVs | 30 |
| Number Of Permutations | 14075 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.032 |
| p-value | 0.961 |
COSMIC
| Number Of Residues | 182 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.546 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
