General Structure Information
| PDB ID | 2pqt |
| HGNC Gene Label(s) | NAT1 |
| Structure Name | human n-acetyltransferase 1 |
| Resolution | 1.78Å |
| Reference | AUTH H.WU,L.DOMBROVSKY,W.TEMPEL,F.MARTIN,P.LOPPNAU,AUTH 2 G.H.GOODFELLOW,D.M.GRANT,A.N.PLOTNIKOVTITL STRUCTURAL BASIS OF SUBSTRATE-BINDING SPECIFICITYTITL 2 OF HUMAN ARYLAMINE N-ACETYLTRANSFERASES.REF J.BIOL.CHEM. V. 282 30189 2007REFN ISSN 0021-9258PMID 17656365DOI 10.1074/JBC.M704138200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 288 |
| Number Of SNVs | 85 |
| Number Of Permutations | 20345 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.041 |
| p-value | 0.579 |
COSMIC
| Number Of Residues | 288 |
| Number Of SNVs | 4 |
| Number Of Permutations | 626 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.167 |
| p-value | 0.44 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 85 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.138 |
| p-value | 0.667 |