1VCA.A | VCAM1

General Structure Information

PDB ID 1vca
HGNC Gene Label(s) VCAM1
Structure Name crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 angstroms resolution
Resolution 1.8Å
Reference AUTH E.Y.JONES,K.HARLOS,M.J.BOTTOMLEY,R.C.ROBINSON,AUTH 2 P.C.DRISCOLL,R.M.EDWARDS,J.M.CLEMENTS,T.J.DUDGEON,AUTH 3 D.I.STUARTTITL CRYSTAL STRUCTURE OF AN INTEGRIN-BINDING FRAGMENTTITL 2 OF VASCULAR CELL ADHESION MOLECULE-1 AT 1.8 ATITL 3 RESOLUTION.REF NATURE V. 373 539 1995REFN ISSN 0028-0836PMID 7531291DOI 10.1038/373539A0

Variant Set Distributions

ExAC Variants

Number Of Residues 199
Number Of SNVs 39
Number Of Permutations 13002
Optimal Distance Threshold 28.0
K Statistic 0.596
p-value 0.285
COSMIC

Number Of Residues 199
Number Of SNVs 3
Number Of Permutations 65
Optimal Distance Threshold 5.0
K Statistic 0.333
p-value 0.061

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 39
Number Of COSMIC SNVs 3
Optimal Distance Threshold 5.0
K Statistic 0.328
p-value 0.206

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants