General Structure Information
| PDB ID | 1k6m |
| HGNC Gene Label(s) | PFKFB1 |
| Structure Name | crystal structure of human liver 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase |
| Resolution | 2.4Å |
| Reference | AUTH Y.H.LEE,Y.LI,K.UYEDA,C.A.HASEMANNTITL TISSUE-SPECIFIC STRUCTURE/FUNCTION DIFFERENTIATION OF THETITL 2 LIVER ISOFORM OFTITL 3 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE.REF J.BIOL.CHEM. V. 278 523 2003REFN ISSN 0021-9258PMID 12379646DOI 10.1074/JBC.M209105200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 432 |
| Number Of SNVs | 83 |
| Number Of Permutations | 47433 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.009 |
| p-value | 0.776 |
COSMIC
| Number Of Residues | 432 |
| Number Of SNVs | 8 |
| Number Of Permutations | 6705 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.036 |
| p-value | 0.042 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 83 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.149 |
| p-value | 0.443 |