General Structure Information
| PDB ID | 1ext |
| HGNC Gene Label(s) | TNFRSF1A |
| Structure Name | extracellular domain of the 55kda tumor necrosis factor receptor. crystallized at ph3.7 in p 21 21 21. |
| Resolution | 1.85Å |
| Reference | AUTH J.H.NAISMITH,T.Q.DEVINE,T.KOHNO,S.R.SPRANGTITL STRUCTURES OF THE EXTRACELLULAR DOMAIN OF THE TYPETITL 2 I TUMOR NECROSIS FACTOR RECEPTOR.REF STRUCTURE V. 4 1251 1996REFN ISSN 0969-2126PMID 8939750DOI 10.1016/S0969-2126(96)00134-7 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 160 |
| Number Of SNVs | 25 |
| Number Of Permutations | 21382 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.017 |
| p-value | 0.963 |
ClinVar
| Number Of Residues | 160 |
| Number Of SNVs | 6 |
| Number Of Permutations | 4079 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.009 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 25 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.283 |
| p-value | 0.084 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
