General Structure Information
| PDB ID | 2h32 |
| HGNC Gene Label(s) | VPREB1 |
| Structure Name | crystal structure of the pre-b cell receptor |
| Resolution | 2.7Å |
| Reference | AUTH A.J.BANKOVICH,S.RAUNSER,Z.S.JUO,T.WALZ,M.M.DAVIS,K.C.GARCIATITL STRUCTURAL INSIGHT INTO PRE-B CELL RECEPTOR FUNCTIONREF SCIENCE V. 316 291 2007REFN ISSN 0036-8075PMID 17431183DOI 10.1126/SCIENCE.1139412 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 111 |
| Number Of SNVs | 38 |
| Number Of Permutations | 8990 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.064 |
| p-value | 0.455 |
COSMIC
| Number Of Residues | 111 |
| Number Of SNVs | 3 |
| Number Of Permutations | 246 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.667 |
| p-value | 0.879 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 38 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.302 |
| p-value | 0.939 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
