General Structure Information
| PDB ID | 3e3b |
| HGNC Gene Label(s) | CSNK2A2 |
| Structure Name | crystal structure of catalytic subunit of human protein kinase ck2alpha prime with a potent indazole-derivative inhibitor |
| Resolution | 3.2Å |
| Reference | AUTH T.NAKANIWA,T.KINOSHITA,Y.SEKIGUCHI,T.TADA,AUTH 2 I.NAKANISHI,K.KITAURA,Y.SUZUKI,H.OHNO,A.HIRASAWA,AUTH 3 G.TSUJIMOTOTITL STRUCTURE OF HUMAN PROTEIN KINASE CK2ALPHA2 WITH ATITL 2 POTENT INDAZOLE-DERIVATIVE INHIBITORREF ACTA CRYSTALLOGR.,SECT.F V. 65 75 2009REFN ESSN 1744-3091PMID 19193990DOI 10.1107/S1744309108043194 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 334 |
| Number Of SNVs | 35 |
| Number Of Permutations | 17000 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.261 |
| p-value | 0.218 |
COSMIC
| Number Of Residues | 334 |
| Number Of SNVs | 4 |
| Number Of Permutations | 37 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.5 |
| p-value | 0.001 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 35 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.976 |
| p-value | 0.001 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
