General Structure Information
| PDB ID | 2iwg |
| HGNC Gene Label(s) | TRIM21 |
| Structure Name | complex between the pryspry domain of trim21 and igg fc |
| Resolution | 2.35Å |
| Reference | AUTH L.C.JAMES,A.H.KEEBLE,Z.KHAN,D.A.RHODES,J.TROWSDALETITL STRUCTURAL BASIS FOR PRYSPRY-MEDIATED TRIPARTITETITL 2 MOTIF (TRIM) PROTEIN FUNCTION.REF PROC.NATL.ACAD.SCI.USA V. 104 6200 2007REFN ISSN 0027-8424PMID 17400754DOI 10.1073/PNAS.0609174104 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 179 |
| Number Of SNVs | 42 |
| Number Of Permutations | 3633 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.184 |
| p-value | 0.154 |
COSMIC

Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC

Pathogenic Proximity Analysis
COSMIC PathProx Analysis

