General Structure Information
| PDB ID | 1b72 |
| HGNC Gene Label(s) | HOXB1 |
| Structure Name | pbx1, homeobox protein hox-b1/dna ternary complex |
| Resolution | 2.35Å |
| Reference | AUTH D.E.PIPER,A.H.BATCHELOR,C.P.CHANG,M.L.CLEARY,AUTH 2 C.WOLBERGERTITL STRUCTURE OF A HOXB1-PBX1 HETERODIMER BOUND TOTITL 2 DNA: ROLE OF THE HEXAPEPTIDE AND A FOURTHTITL 3 HOMEODOMAIN HELIX IN COMPLEX FORMATION.REF CELL(CAMBRIDGE,MASS.) V. 96 587 1999REFN ISSN 0092-8674PMID 10052460DOI 10.1016/S0092-8674(00)80662-5 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 68 |
| Number Of SNVs | 11 |
| Number Of Permutations | 1776 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.273 |
| p-value | 0.533 |
COSMIC
| Number Of Residues | 68 |
| Number Of SNVs | 3 |
| Number Of Permutations | 77 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 11 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | -0.303 |
| p-value | 0.595 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
