General Structure Information
| PDB ID | 1bla |
| HGNC Gene Label(s) | FGF2 |
| Structure Name | basic fibroblast growth factor (fgf-2) mutant with cys 78 replaced by ser and cys 96 replaced by ser, nmr |
| Resolution | -1.0Å |
| Reference | AUTH F.J.MOY,A.P.SEDDON,P.BOHLEN,R.POWERSTITL HIGH-RESOLUTION SOLUTION STRUCTURE OF BASICTITL 2 FIBROBLAST GROWTH FACTOR DETERMINED BYTITL 3 MULTIDIMENSIONAL HETERONUCLEAR MAGNETIC RESONANCETITL 4 SPECTROSCOPY.REF BIOCHEMISTRY V. 35 13552 1996REFN ISSN 0006-2960PMID 8885834DOI 10.1021/BI961260P |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 155 |
| Number Of SNVs | 31 |
| Number Of Permutations | 2559 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.041 |
| p-value | 0.683 |
COSMIC
| Number Of Residues | 155 |
| Number Of SNVs | 3 |
| Number Of Permutations | 163 |
| Optimal Distance Threshold | 32.0 |
| K Statistic | 0.667 |
| p-value | 0.356 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 31 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.469 |
| p-value | 0.153 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
