1G83.B | FYN

General Structure Information

PDB ID 1g83
HGNC Gene Label(s) FYN
Structure Name crystal structure of fyn sh3-sh2
Resolution 2.6Å
Reference AUTH S.T.AROLD,T.S.ULMER,T.D.MULHERN,J.M.WERNER,AUTH 2 J.E.LADBURY,I.D.CAMPBELL,M.E.NOBLETITL THE ROLE OF THE SRC HOMOLOGY 3-SRC HOMOLOGY 2TITL 2 INTERFACE IN THE REGULATION OF SRC KINASES.REF J.BIOL.CHEM. V. 276 17199 2001REFN ISSN 0021-9258PMID 11278857DOI 10.1074/JBC.M011185200

Variant Set Distributions

ExAC Variants

Number Of Residues 161
Number Of SNVs 18
Number Of Permutations 3385
Optimal Distance Threshold 16.0
K Statistic 0.209
p-value 0.24
COSMIC

Number Of Residues 161
Number Of SNVs 3
Number Of Permutations 162
Optimal Distance Threshold 16.0
K Statistic 0.667
p-value 0.301

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 18
Number Of COSMIC SNVs 3
Optimal Distance Threshold 16.0
K Statistic 0.458
p-value 0.313

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants