4ADF.K | CSF1

General Structure Information

PDB ID 4adf
HGNC Gene Label(s) CSF1
Structure Name crystal structure of the human colony-stimulating factor 1 (hcsf-1) cytokine in complex with the viral receptor barf1
Resolution 4.4Å
Reference AUTH J.ELEGHEERT,N.BRACKE,P.POULIOT,I.GUTSCHE,A.V.SHKUMATOV,AUTH 2 N.TARBOURIECH,K.VERSTRAETE,A.BEKAERT,W.P.BURMEISTER,AUTH 3 D.I.SVERGUN,B.N.LAMBRECHT,B.VERGAUWEN,S.N.SAVVIDESTITL ALLOSTERIC COMPETITIVE INACTIVATION OF HEMATOPOIETIC CSF-1TITL 2 SIGNALING BY THE VIRAL DECOY RECEPTOR BARF1.REF NAT.STRUCT.MOL.BIOL. V. 19 938 2012REFN ISSN 1545-9993PMID 22902366DOI 10.1038/NSMB.2367

Variant Set Distributions

ExAC Variants

Number Of Residues 143
Number Of SNVs 30
Number Of Permutations 10119
Optimal Distance Threshold 6.0
K Statistic 0.044
p-value 0.984

Mapped Variants

[+] ExAC Missense Variants