General Structure Information
| PDB ID | 4glp |
| HGNC Gene Label(s) | CD14 |
| Structure Name | the crystal structure of soluble human cd14 reveals a bent solenoid with a hydrophobic amino-terminal pocket. |
| Resolution | 4.0Å |
| Reference | AUTH S.L.KELLEY,T.LUKK,S.K.NAIR,R.I.TAPPINGTITL THE CRYSTAL STRUCTURE OF HUMAN SOLUBLE CD14 REVEALS A BENTTITL 2 SOLENOID WITH A HYDROPHOBIC AMINO-TERMINAL POCKET.REF J.IMMUNOL. V. 190 1304 2013REFN ISSN 0022-1767PMID 23264655DOI 10.4049/JIMMUNOL.1202446 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 310 |
| Number Of SNVs | 105 |
| Number Of Permutations | 18133 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.025 |
| p-value | 0.821 |
COSMIC
| Number Of Residues | 310 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1492 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.267 |
| p-value | 0.632 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 105 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | -0.105 |
| p-value | 0.797 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
