General Structure Information
| PDB ID | 2vct |
| HGNC Gene Label(s) | GSTA2 |
| Structure Name | glutathione transferase a2-2 in complex with delta-4- andostrene-3-17-dione |
| Resolution | 2.1Å |
| Reference | AUTH K.TARS,B.OLIN,B.MANNERVIKTITL STRUCTURAL BASIS FOR FEATURING OF STEROIDTITL 2 ISOMERASE ACTIVITY IN ALPHA CLASS GLUTATHIONETITL 3 TRANSFERASES.REF J.MOL.BIOL. V. 397 332 2010REFN ISSN 0022-2836PMID 20083122DOI 10.1016/J.JMB.2010.01.023 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 221 |
| Number Of SNVs | 66 |
| Number Of Permutations | 24732 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.219 |
| p-value | 0.347 |
COSMIC
| Number Of Residues | 221 |
| Number Of SNVs | 8 |
| Number Of Permutations | 6216 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.286 |
| p-value | 0.051 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 66 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.148 |
| p-value | 0.498 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
