General Structure Information
| PDB ID | 1kb4 |
| HGNC Gene Label(s) | VDR |
| Structure Name | crystal structure of vdr dna-binding domain bound to a canonical direct repeat with three base pair spacer (dr3) response element |
| Resolution | 2.8Å |
| Reference | AUTH P.L.SHAFFER,D.T.GEWIRTHTITL STRUCTURAL BASIS OF VDR-DNA INTERACTIONS ON DIRECTTITL 2 REPEAT RESPONSE ELEMENTS.REF EMBO J. V. 21 2242 2002REFN ISSN 0261-4189PMID 11980721DOI 10.1093/EMBOJ/21.9.2242 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 99 |
| Number Of SNVs | 29 |
| Number Of Permutations | 24026 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.567 |
| p-value | 0.423 |
ClinVar
| Number Of Residues | 99 |
| Number Of SNVs | 5 |
| Number Of Permutations | 2356 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.7 |
| p-value | 0.036 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 29 |
| Number Of ClinVar SNVs | 5 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.446 |
| p-value | 0.083 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
