General Structure Information
| PDB ID | 1kyn |
| HGNC Gene Label(s) | CTSG |
| Structure Name | cathepsin-g |
| Resolution | 3.5Å |
| Reference | AUTH M.N.GRECO,M.J.HAWKINS,E.T.POWELL,H.R.ALMOND JR.,AUTH 2 T.W.CORCORAN,L.DE GARAVILLA,J.A.KAUFFMAN,R.RECACHA,AUTH 3 D.CHATTOPADHYAY,P.ANDRADE-GORDON,B.E.MARYANOFFTITL NONPEPTIDE INHIBITORS OF CATHEPSIN G: OPTIMIZATIONTITL 2 OF A NOVEL BETA-KETOPHOSPHONIC ACID LEAD BYTITL 3 STRUCTURE-BASED DRUG DESIGN.REF J.AM.CHEM.SOC. V. 124 3810 2002REFN ISSN 0002-7863PMID 11942800DOI 10.1021/JA017506H |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 221 |
| Number Of SNVs | 47 |
| Number Of Permutations | 15821 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.039 |
| p-value | 0.748 |
COSMIC
| Number Of Residues | 221 |
| Number Of SNVs | 7 |
| Number Of Permutations | 866 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.048 |
| p-value | 0.46 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.29 |
| p-value | 0.707 |