General Structure Information
| PDB ID | 1cvs |
| HGNC Gene Label(s) | FGFR1 |
| Structure Name | crystal structure of a dimeric fgf2-fgfr1 complex |
| Resolution | 2.8Å |
| Reference | AUTH A.N.PLOTNIKOV,J.SCHLESSINGER,S.R.HUBBARD,AUTH 2 M.MOHAMMADITITL STRUCTURAL BASIS FOR FGF RECEPTOR DIMERIZATION ANDTITL 2 ACTIVATION.REF CELL(CAMBRIDGE,MASS.) V. 98 641 1999REFN ISSN 0092-8674PMID 10490103DOI 10.1016/S0092-8674(00)80051-3 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 211 |
| Number Of SNVs | 25 |
| Number Of Permutations | 9376 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.02 |
| p-value | 0.58 |
ClinVar
| Number Of Residues | 211 |
| Number Of SNVs | 9 |
| Number Of Permutations | 3480 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.111 |
| p-value | 0.314 |
COSMIC
| Number Of Residues | 211 |
| Number Of SNVs | 4 |
| Number Of Permutations | 83 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.167 |
| p-value | 0.905 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 25 |
| Number Of ClinVar SNVs | 9 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | -0.106 |
| p-value | 0.5 |
Cosmic vs. ExAC
