General Structure Information
| PDB ID | 4h5n |
| HGNC Gene Label(s) | HSPA8 |
| Structure Name | hsc70 nbd with po4, na, cl |
| Resolution | 1.86Å |
| Reference | AUTH Z.ZHANG,J.CELLITTI,P.TERIETE,M.PELLECCHIA,B.STECTITL NEW CRYSTAL STRUCTURES OF HSC-70 ATP BINDING DOMAIN CONFIRMTITL 2 THE ROLE OF INDIVIDUAL BINDING POCKETS AND SUGGEST A NEWTITL 3 METHOD OF INHIBITION.REF BIOCHIMIE V. 108 186 2015REFN ISSN 0300-9084PMID 25433210DOI 10.1016/J.BIOCHI.2014.11.012 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 382 |
| Number Of SNVs | 28 |
| Number Of Permutations | 15656 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.05 |
| p-value | 0.578 |
COSMIC
| Number Of Residues | 382 |
| Number Of SNVs | 15 |
| Number Of Permutations | 9830 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.162 |
| p-value | 0.496 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 28 |
| Number Of COSMIC SNVs | 15 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.083 |
| p-value | 0.694 |