General Structure Information
| PDB ID | 3mjg |
| HGNC Gene Label(s) | PDGFRB |
| Structure Name | the structure of a platelet derived growth factor receptor complex |
| Resolution | 2.3Å |
| Reference | AUTH A.H.SHIM,H.LIU,P.J.FOCIA,X.CHEN,P.C.LIN,X.HETITL STRUCTURES OF A PLATELET-DERIVED GROWTH FACTOR/PROPEPTIDETITL 2 COMPLEX AND A PLATELET-DERIVED GROWTH FACTOR/RECEPTORTITL 3 COMPLEX.REF PROC.NATL.ACAD.SCI.USA V. 107 11307 2010REFN ISSN 0027-8424PMID 20534510DOI 10.1073/PNAS.1000806107 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 274 |
| Number Of SNVs | 72 |
| Number Of Permutations | 47610 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.06 |
| p-value | 0.637 |
COSMIC
| Number Of Residues | 274 |
| Number Of SNVs | 4 |
| Number Of Permutations | 709 |
| Optimal Distance Threshold | 32.0 |
| K Statistic | 0.167 |
| p-value | 0.435 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 72 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 38.0 |
| K Statistic | -0.384 |
| p-value | 0.122 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
