General Structure Information
| PDB ID | 2h4m |
| HGNC Gene Label(s) | HNRNPA1 |
| Structure Name | karyopherin beta2/transportin-m9nls |
| Resolution | 3.05Å |
| Reference | AUTH B.J.LEE,A.E.CANSIZOGLU,T.H.LOUIS,Z.ZHANG,Y.M.CHOOKTITL RULES FOR NUCLEAR LOCALIZATION SEQUENCETITL 2 RECOGNITION BY KARYOPHERIN BETA 2.REF CELL(CAMBRIDGE,MASS.) V. 126 543 2006REFN ISSN 0092-8674PMID 16901787DOI 10.1016/J.CELL.2006.05.049 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 27 |
| Number Of SNVs | 5 |
| Number Of Permutations | 351 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.7 |
| p-value | 0.103 |
ClinVar
| Number Of Residues | 27 |
| Number Of SNVs | 10 |
| Number Of Permutations | 803 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.067 |
| p-value | 0.929 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 5 |
| Number Of ClinVar SNVs | 10 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | -0.311 |
| p-value | 0.139 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
