2COK.A | PARP1

PDB ID	2cok
HGNC Gene Label(s)	PARP1
Structure Name	solution structure of brct domain of poly(adp-ribose) polymerase-1
Resolution	-1.0Å
Reference	AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF BRCT DOMAIN OFTITL 2 POLY(ADP-RIBOSE) POLYMERASE-1REF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
1:226568894		N>S	A:13	(-2.94, 6.18, -12.08)
1:226568891		M>T	A:14	(-0.66, 3.54, -7.86)
1:226568861	rs150379323	R>Q	A:24	(-3.19, 8.86, 9.57)
1:226568862		R>W	A:24	(-3.19, 8.86, 9.57)
1:226568830		E>D	A:34	(-7.75, 9.13, -2.74)
1:226568823		G>R	A:37	(-3.73, 10.28, -6.35)
1:226568816		K>R	A:39	(-8.03, 5.72, -6.75)
1:226568810	COSM4028710	T>M	A:41	(-8.02, -1.39, -3.20)
1:226568811		T>S	A:41	(-8.02, -1.39, -3.20)
1:226568804	COSM1645337	T>M	A:43	(-9.15, -6.84, -4.32)
1:226568798	rs147711929	N>S	A:45	(-5.51, -10.09, -6.94)
1:226568781		I>V	A:51	(-0.07, 0.85, 3.22)
1:226568769		K>E	A:55	(2.40, -7.34, 14.92)
1:226567847	rs145185569	N>S	A:61	(-4.59, -14.13, 7.14)
1:226567842		K>Q	A:63	(-7.42, -10.94, 5.16)
1:226567838		M>T	A:64	(-0.88, -10.38, 4.15)
1:226567831		E>D	A:66	(-5.02, -12.24, -1.68)
1:226567832		E>V	A:66	(-5.02, -12.24, -1.68)
1:226567827		K>E	A:68	(3.24, -14.32, -0.69)
1:226567817	rs374389375	N>S	A:71	(4.48, -10.57, -6.03)
1:226567811	rs552397377	R>Q	A:73	(7.07, -3.33, -3.33)
1:226567806		V>L	A:75	(4.98, -0.48, 2.03)
1:226567798		E>D	A:77	(1.20, 4.36, 7.31)
1:226567799		E>V	A:77	(1.20, 4.36, 7.31)
1:226567793	rs533318843	F>C	A:79	(4.71, 4.83, 1.29)
1:226567785		D>N	A:82	(7.64, 9.54, 3.20)
1:226567782		V>I	A:83	(4.61, 9.20, -0.88)
1:226567776	rs149332554	A>S	A:85	(6.96, 14.30, 2.97)
1:226567772		S>F	A:86	(9.72, 12.08, 0.43)
1:226567757		Q>L	A:91	(10.81, 1.52, -7.18)
1:226567724	rs138072805	W>S	A:102	(5.86, -10.31, -0.46)
1:226567715		E>A	A:105	(9.72, -7.42, -11.71)
1:226567716		E>K	A:105	(9.72, -7.42, -11.71)
1:226567712		V>G	A:106	(5.61, -11.19, -10.55)

2COK.A | PARP1.