General Structure Information
| PDB ID | 1ni6 |
| HGNC Gene Label(s) | HMOX1 |
| Structure Name | comparisions of the heme-free and-bound crystal structures of human heme oxygenase-1 |
| Resolution | 2.1Å |
| Reference | AUTH L.LAD,D.J.SCHULLER,H.SHIMIZU,J.FRIEDMAN,H.LI,AUTH 2 P.R.ORTIZ DE MONTELLANO,T.L.POULOSTITL COMPARISON OF THE HEME-FREE AND -BOUND CRYSTALTITL 2 STRUCTURES OF HUMAN HEME OXYGENASE-1REF J.BIOL.CHEM. V. 278 7834 2003REFN ISSN 0021-9258PMID 12500973DOI 10.1074/JBC.M211450200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 213 |
| Number Of SNVs | 71 |
| Number Of Permutations | 27331 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.066 |
| p-value | 0.265 |
COSMIC
| Number Of Residues | 213 |
| Number Of SNVs | 4 |
| Number Of Permutations | 551 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.167 |
| p-value | 0.83 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 71 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | -0.332 |
| p-value | 0.33 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
