2L86.A | IAPP

General Structure Information

PDB ID 2l86
HGNC Gene Label(s) IAPP
Structure Name solution nmr structure of human amylin in sds micelles at ph 7.3
Resolution -1.0Å
Reference AUTH R.P.NANGA,J.R.BRENDER,S.VIVEKANANDAN,A.RAMAMOORTHYTITL STRUCTURE AND MEMBRANE ORIENTATION OF IAPP IN ITS NATIVELYTITL 2 AMIDATED FORM AT PHYSIOLOGICAL PH IN A MEMBRANE ENVIRONMENT.REF BIOCHIM.BIOPHYS.ACTA V.1808 2337 2011REFN ISSN 0006-3002PMID 21723249DOI 10.1016/J.BBAMEM.2011.06.012

Variant Set Distributions

ExAC Variants

Number Of Residues 37
Number Of SNVs 12
Number Of Permutations 878
Optimal Distance Threshold 6.0
K Statistic 0.076
p-value 0.967

Mapped Variants

[+] ExAC Missense Variants