General Structure Information
| PDB ID | 1hve |
| HGNC Gene Label(s) | ANXA5 |
| Structure Name | structural and electrophysiological analysis of annexin v mutants. mutagenesis of human annexin v, an in vitro voltage-gated calcium channel, provides information about the structural features of the ion pathway, the voltage sensor and the ion selectivity filter |
| Resolution | 2.3Å |
| Reference | AUTH A.BURGER,D.VOGES,P.DEMANGE,C.R.PEREZ,R.HUBER,AUTH 2 R.BERENDESTITL STRUCTURAL AND ELECTROPHYSIOLOGICAL ANALYSIS OFTITL 2 ANNEXIN V MUTANTS. MUTAGENESIS OF HUMAN ANNEXIN V,TITL 3 AN IN VITRO VOLTAGE-GATED CALCIUM CHANNEL,TITL 4 PROVIDES INFORMATION ABOUT THE STRUCTURAL FEATURESTITL 5 OF THE ION PATHWAY, THE VOLTAGE SENSOR AND THE IONTITL 6 SELECTIVITY FILTERREF J.MOL.BIOL. V. 237 479 1994REFN ISSN 0022-2836PMID 8151707DOI 10.1006/JMBI.1994.1249 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 312 |
| Number Of SNVs | 68 |
| Number Of Permutations | 41279 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.362 |
| p-value | 0.516 |