General Structure Information
| PDB ID | 1il8 |
| HGNC Gene Label(s) | IL8 |
| Structure Name | three-dimensional structure of interleukin 8 in solution |
| Resolution | -1.0Å |
| Reference | AUTH G.M.CLORE,E.APPELLA,M.YAMADA,K.MATSUSHIMA,AUTH 2 A.M.GRONENBORNTITL THREE-DIMENSIONAL STRUCTURE OF INTERLEUKIN 8 INTITL 2 SOLUTION.REF BIOCHEMISTRY V. 29 1689 1990REFN ISSN 0006-2960PMID 2184886DOI 10.1021/BI00459A004 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 71 |
| Number Of SNVs | 12 |
| Number Of Permutations | 3768 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.015 |
| p-value | 0.046 |
COSMIC
| Number Of Residues | 71 |
| Number Of SNVs | 4 |
| Number Of Permutations | 995 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.167 |
| p-value | 0.62 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 12 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.152 |
| p-value | 0.738 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
