General Structure Information
| PDB ID | 2cso |
| HGNC Gene Label(s) | PLEK |
| Structure Name | solution structure of the dep domain of human pleckstrin |
| Resolution | -1.0Å |
| Reference | AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE DEP DOMAIN OF HUMANTITL 2 PLECKSTRINREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 114 |
| Number Of SNVs | 38 |
| Number Of Permutations | 21154 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.154 |
| p-value | 0.554 |
COSMIC
| Number Of Residues | 114 |
| Number Of SNVs | 4 |
| Number Of Permutations | 95 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.167 |
| p-value | 0.767 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 38 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | -0.508 |
| p-value | 0.346 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
