General Structure Information
| PDB ID | 2dh3 |
| HGNC Gene Label(s) | SLC3A2 |
| Structure Name | crystal structure of human ed-4f2hc |
| Resolution | 2.8Å |
| Reference | AUTH J.FORT,L.R.DE LA BALLINA,H.E.BURGHARDT,C.FERRER-COSTA,AUTH 2 J.TURNAY,C.FERRER-ORTA,I.USON,A.ZORZANO,J.FERNANDEZ-RECIO,AUTH 3 M.OROZCO,M.A.LIZARBE,I.FITA,M.PALACINTITL THE STRUCTURE OF HUMAN 4F2HC ECTODOMAIN PROVIDES A MODEL FORTITL 2 HOMODIMERIZATION AND ELECTROSTATIC INTERACTION WITH PLASMATITL 3 MEMBRANE.REF J.BIOL.CHEM. V. 282 31444 2007REFN ISSN 0021-9258PMID 17724034DOI 10.1074/JBC.M704524200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 416 |
| Number Of SNVs | 98 |
| Number Of Permutations | 17652 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.013 |
| p-value | 0.426 |
COSMIC
| Number Of Residues | 416 |
| Number Of SNVs | 5 |
| Number Of Permutations | 376 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.2 |
| p-value | 0.391 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 98 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.409 |
| p-value | 0.249 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
