General Structure Information
| PDB ID | 3qum |
| HGNC Gene Label(s) | KLK3 |
| Structure Name | crystal structure of human prostate specific antigen (psa) in fab sandwich with a high affinity and a pca selective antibody |
| Resolution | 3.2Å |
| Reference | AUTH E.A.STURA,B.H.MULLER,M.BOSSUS,S.MICHEL,C.JOLIVET-REYNAUD,AUTH 2 F.DUCANCELTITL CRYSTAL STRUCTURE OF HUMAN PROSTATE-SPECIFIC ANTIGEN IN ATITL 2 SANDWICH ANTIBODY COMPLEX.REF J.MOL.BIOL. V. 414 530 2011REFN ISSN 0022-2836PMID 22037582DOI 10.1016/J.JMB.2011.10.007 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 223 |
| Number Of SNVs | 69 |
| Number Of Permutations | 6879 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.039 |
| p-value | 0.717 |
COSMIC
| Number Of Residues | 223 |
| Number Of SNVs | 8 |
| Number Of Permutations | 1289 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.143 |
| p-value | 0.226 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 69 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.068 |
| p-value | 0.886 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
