General Structure Information
| PDB ID | 2arv |
| HGNC Gene Label(s) | INHBA |
| Structure Name | structure of human activin a |
| Resolution | 2.0Å |
| Reference | AUTH A.E.HARRINGTON,S.A.MORRIS-TRIGGS,B.T.RUOTOLO,C.V.ROBINSON,AUTH 2 S.OHNUMA,M.HYVONENTITL STRUCTURAL BASIS FOR THE INHIBITION OF ACTIVIN SIGNALLING BYTITL 2 FOLLISTATINREF EMBO J. V. 25 1035 2006REFN ISSN 0261-4189PMID 16482217DOI 10.1038/SJ.EMBOJ.7601000 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 116 |
| Number Of SNVs | 10 |
| Number Of Permutations | 1667 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.111 |
| p-value | 0.013 |
COSMIC
| Number Of Residues | 116 |
| Number Of SNVs | 4 |
| Number Of Permutations | 532 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.5 |
| p-value | 0.394 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 10 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.289 |
| p-value | 0.644 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
