General Structure Information
| PDB ID | 1jiq |
| HGNC Gene Label(s) | GPI |
| Structure Name | crystal structure of human autocrine motility factor |
| Resolution | 1.9Å |
| Reference | AUTH N.TANAKA,A.HAGA,H.UEMURA,H.AKIYAMA,T.FUNASAKA,AUTH 2 H.NAGASE,A.RAZ,K.T.NAKAMURATITL INHIBITION MECHANISM OF CYTOKINE ACTIVITY OF HUMANTITL 2 AUTOCRINE MOTILITY FACTOR EXAMINED BY CRYSTALTITL 3 STRUCTURE ANALYSES AND SITE-DIRECTED MUTAGENESISTITL 4 STUDIES.REF J.MOL.BIOL. V. 318 985 2002REFN ISSN 0022-2836PMID 12054796DOI 10.1016/S0022-2836(02)00186-9 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 557 |
| Number Of SNVs | 122 |
| Number Of Permutations | 69363 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.229 |
| p-value | 0.172 |
ClinVar
| Number Of Residues | 557 |
| Number Of SNVs | 9 |
| Number Of Permutations | 6432 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.139 |
| p-value | 0.93 |
COSMIC
| Number Of Residues | 557 |
| Number Of SNVs | 3 |
| Number Of Permutations | 330 |
| Optimal Distance Threshold | 63.0 |
| K Statistic | 0.667 |
| p-value | 0.246 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 122 |
| Number Of ClinVar SNVs | 9 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.077 |
| p-value | 0.751 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 122 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 40.0 |
| K Statistic | -0.616 |
| p-value | 0.12 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
COSMIC PathProx Analysis
