General Structure Information
| PDB ID | 1nfa |
| HGNC Gene Label(s) | NFATC1 |
| Structure Name | human transcription factor nfatc dna binding domain, nmr, 10 structures |
| Resolution | -1.0Å |
| Reference | AUTH S.A.WOLFE,P.ZHOU,V.DOTSCH,L.CHEN,A.YOU,S.N.HO,AUTH 2 G.R.CRABTREE,G.WAGNER,G.L.VERDINETITL UNUSUAL REL-LIKE ARCHITECTURE IN THE DNA-BINDINGTITL 2 DOMAIN OF THE TRANSCRIPTION FACTOR NFATC.REF NATURE V. 385 172 1997REFN ISSN 0028-0836PMID 8990122DOI 10.1038/385172A0 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 176 |
| Number Of SNVs | 44 |
| Number Of Permutations | 10213 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.038 |
| p-value | 0.626 |
COSMIC
| Number Of Residues | 176 |
| Number Of SNVs | 5 |
| Number Of Permutations | 234 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.3 |
| p-value | 0.117 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 44 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.228 |
| p-value | 0.305 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
