General Structure Information
| PDB ID | 2oct |
| HGNC Gene Label(s) | CSTB |
| Structure Name | stefin b (cystatin b) tetramer |
| Resolution | 1.4Å |
| Reference | AUTH S.JENKO KOKALJ,G.GUNCAR,I.STERN,G.MORGAN,S.RABZELJ,M.KENIG,AUTH 2 R.A.STANIFORTH,J.P.WALTHO,E.ZEROVNIK,D.TURKTITL ESSENTIAL ROLE OF PROLINE ISOMERIZATION IN STEFIN B TETRAMERTITL 2 FORMATION.REF J.MOL.BIOL. V. 366 1569 2007REFN ISSN 0022-2836PMID 17217964DOI 10.1016/J.JMB.2006.12.025 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 95 |
| Number Of SNVs | 25 |
| Number Of Permutations | 10260 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.273 |
| p-value | 0.044 |
ClinVar
| Number Of Residues | 95 |
| Number Of SNVs | 3 |
| Number Of Permutations | 190 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 1.0 |
| p-value | 0.067 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 25 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.703 |
| p-value | 0.134 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
