General Structure Information
| PDB ID | 2uzp |
| HGNC Gene Label(s) | PRKCG |
| Structure Name | crystal structure of the c2 domain of human protein kinase c gamma. |
| Resolution | 2.0Å |
| Reference | AUTH A.C.W.PIKE,A.AMOS,C.JOHANSSON,F.SOBOTT,P.SAVITSKY,AUTH 2 G.BERRIDGE,O.FEDOROV,C.UMEANO,F.GORREC,G.BUNKOCZI,AUTH 3 J.DEBRECZENI,F.VON DELFT,C.H.ARROWSMITH,A.EDWARDS,J.WEIGELT,AUTH 4 M.SUNDSTROM,S.KNAPPTITL CRYSTAL STRUCTURE OF C2 DOMAIN OF PROTEIN KINASE C GAMMAREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 140 |
| Number Of SNVs | 24 |
| Number Of Permutations | 7765 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.004 |
| p-value | 0.251 |
COSMIC
| Number Of Residues | 140 |
| Number Of SNVs | 6 |
| Number Of Permutations | 667 |
| Optimal Distance Threshold | 4.0 |
| K Statistic | 0.067 |
| p-value | 0.37 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 24 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.198 |
| p-value | 0.637 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
