General Structure Information
| PDB ID | 4der |
| HGNC Gene Label(s) | TTR |
| Structure Name | crystal structure of the wild type ttr binding apigenin (ttrwt:api) |
| Resolution | 1.9Å |
| Reference | AUTH D.B.TRIVELLA,C.V.DOS REIS,L.M.LIMA,D.FOGUEL,I.POLIKARPOVTITL FLAVONOID INTERACTIONS WITH HUMAN TRANSTHYRETIN: COMBINEDTITL 2 STRUCTURAL AND THERMODYNAMIC ANALYSIS.REF J.STRUCT.BIOL. V. 180 143 2012REFN ISSN 1047-8477PMID 22842046DOI 10.1016/J.JSB.2012.07.008 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 116 |
| Number Of SNVs | 29 |
| Number Of Permutations | 2339 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.007 |
| p-value | 0.277 |
ClinVar
| Number Of Residues | 116 |
| Number Of SNVs | 38 |
| Number Of Permutations | 2973 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.11 |
| p-value | 0.047 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 29 |
| Number Of ClinVar SNVs | 36 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.044 |
| p-value | 0.092 |