General Structure Information
| PDB ID | 3ghg |
| HGNC Gene Label(s) | FGA |
| Structure Name | crystal structure of human fibrinogen |
| Resolution | 2.9Å |
| Reference | AUTH J.M.KOLLMAN,L.PANDI,M.R.SAWAYA,M.RILEY,R.F.DOOLITTLETITL CRYSTAL STRUCTURE OF HUMAN FIBRINOGEN.REF BIOCHEMISTRY V. 48 3877 2009REFN ISSN 0006-2960PMID 19296670DOI 10.1021/BI802205G |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 174 |
| Number Of SNVs | 49 |
| Number Of Permutations | 29829 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.099 |
| p-value | 0.18 |
COSMIC
| Number Of Residues | 174 |
| Number Of SNVs | 10 |
| Number Of Permutations | 5014 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.067 |
| p-value | 0.293 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 49 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 69.0 |
| K Statistic | 0.312 |
| p-value | 0.235 |