2VOO.A | SSB – ASTRID

2VOO.A | SSB

PDB ID	2voo
HGNC Gene Label(s)	SSB
Structure Name	crystal structure of n-terminal domains of human la protein complexed with rna oligomer uuuuuuuu
Resolution	1.8Å
Reference	AUTH O.KOTIK-KOGAN,E.R.VALENTINE,D.SANFELICE,M.R.CONTE,AUTH 2 S.CURRYTITL STRUCTURAL ANALYSIS REVEALS CONFORMATIONALTITL 2 PLASTICITY IN THE RECOGNITION OF RNA 3 ENDS BYTITL 3 THE HUMAN LA PROTEIN.REF STRUCTURE V. 16 852 2008REFN ISSN 0969-2126PMID 18547518DOI 10.1016/J.STR.2008.02.021

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
2:170657505	rs146485470	A>V	A:12	(5.61, -43.23, -16.68)
2:170662003	COSM3787890	N>S	A:29	(-7.20, -44.08, 1.65)
2:170662014		D>N	A:33	(-5.75, -47.04, 5.74)
2:170662039		K>T	A:41	(-0.12, -43.73, 15.00)
2:170662074	rs532347388	I>V	A:53	(7.59, -52.56, -0.80)
2:170662207		I>T	A:68	(9.96, -45.10, -4.86)
2:170662233	rs548069992	A>T	A:77	(1.73, -32.61, -5.35)
2:170662236		E>Q	A:78	(4.89, -31.11, -3.59)
2:170662239		L>F	A:79	(1.32, -34.94, -0.45)
2:170662244	rs141623414	M>I	A:80	(4.48, -36.99, 0.10)
2:170662281	rs568279000	P>S	A:93	(3.42, -31.96, 8.16)
2:170662284		S>G	A:94	(2.01, -28.87, 5.78)
2:170662312		E>G	A:103	(-20.28, -28.98, 3.62)
2:170662326		V>L	A:108	(-18.03, -36.11, -1.13)
2:170662333	rs537120356	N>S	A:110	(-23.00, -33.85, -3.94)
2:170662345	rs377101371	Y>F	A:114	(-24.30, -46.87, -9.22)
2:170662347	rs557065020	I>V	A:115	(-21.08, -46.67, -12.61)
2:170663307		T>A	A:120	(-17.30, -59.52, -13.44)
2:170663328	rs372066287	I>L	A:127	(-12.34, -48.96, -14.45)
2:170663340	rs200789540	L>I	A:131	(-12.76, -43.03, -15.82)
2:170663368		I>T	A:140	(-12.28, -46.02, -8.30)
2:170663394	rs546270676	A>S	A:149	(-16.80, -60.53, -6.13)
2:170663398		F>S	A:150	(-16.61, -56.31, -9.78)
2:170663523		K>E	A:166	(-19.76, -33.32, -18.32)
2:170663538	rs186344908	P>S	A:171	(-25.80, -39.43, -23.18)
2:170663564		D>E	A:179	(-25.69, -49.79, -21.28)
2:170663572		I>T	A:182	(-24.87, -43.44, -14.86)
2:170663579		F>L	A:184	(-25.48, -38.08, -9.10)